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    Tapentadol belongs to a class of pain relievers known as opioid analgesics also known as narcotic analgesics that act on the central nervous system.

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    How Tapentadol works Tapentadol decreases the perception of pain by blocking the transmission of pain signals to the brain.

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    Current pharmacological treatment options commonly used for moderate-to-severe pain include anticonvulsants, antidepressants, nonsteroidal anti-inflammatory agents NSAIDs, tramadol Ul-tram, PriCara, and opioids.

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    Fatal overdose may occur when opiates are combined with other depressants such as benzodiazepines, barbiturates, gabapentinoids, thienodiazepines, alcohol or other GABAergic substances.

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    Management of pain or neuropathic pain associated with diabetic peripheral neuropathy DPN severe enough to require daily, around-the-clock, long-term analgesia for which alternative treatment options are inadequate.

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