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Isotretinoin is used to treat severe types of acne, such as nodular or inflammatory acne, where other medications with less potential for severe side effects have failed to help.
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Peripheral actions include nausea, vomiting and postural hypotension, although these are lessened by the use of carbidopa. Central side effects with long-term therapy of levodopa can be serious enough for treatment to be stopped.
Authored by Dr. Gregory Obara, MD