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Generics of the powerful medicine have been available since and now dominate the market, Roche said. Roche said the move was not done for safety or efficacy reasons and was purchase accutane generic to have any impact on earnings. The last date for distribution in the United States was June While powerful at clearing acne, the drug is linked to severe birth defects if taken during pregnancy, so physicians and patients must abide by a strict risk management program.

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The acne drug Accutane is one of the most dangerous products on the market today. The drug causes serious side-effects, most notably birth defects. This combination—unique efficacy coupled with unique risk—has posed a serious challenge for the Food and Drug Administration FDA. Over the past two decades, FDA has grappled with how manage the completely preventable but persistently serious problem of Accutane-induced birth defects. On several occasions, the product spurred FDA to take unprecedented regulatory action.

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Isotretinoin is used to treat severe types of acne, such as nodular or inflammatory acne, where other medications with less potential for severe side effects have failed to help. Your doctor will adjust your daily dose after the initial treatment to between 0. Health Canada has issued new restrictions concerning the use of isotretinoin. Birth Control: Isotretinoin causes birth defects in a large percentage of babies born to women who take this medication during pregnancy.