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Within a few years, six million Americans were taking it. By the end of the year the drug was pulled from the market. Three years later, Meridia, a top-selling weight loss drug in Canada, was voluntarily withdrawn by its makers over an increased risk of heart attack, stroke and cardiovascular death. Now, however, the pharmaceutical industry is bringing anti-obesity drugs back to the market. Several have been approved in the last few years, and many more are likely to come.
Phenylpropanolamine PPA is a sympathomimetic agent which is used as a decongestant and appetite suppressant. In veterinary medicine, it is used to control urinary incontinence in dogs. There are four optical isomers of PPA: dextro- and levo-norephedrine, and dextro- and levo-norpseudoephedrine. Exogenous compounds in this family are degraded too rapidly by monoamine oxidase to be active at all but the highest doses. In Canada, it was withdrawn from the market on 31 May PPA acts primarily as a selective norepinephrine releasing agent.
Hence, the administration of the medication requires vigilant supervision. This cautionary fact is highlighted as the pill is a classified drug that exhibits potential for abuse. Doctors will have to assess the condition, and it is considered to be a risk for babies widely. Obesity is not a joke as it poses serious life-threatening conditions as time passes by. Life progresses towards betterment only when comfort and convenience are compromised at times. For that to happen, one must indulge in a better lifestyle routine that includes exercise, diet, and proper medication. The only way to discard obesity is by revamping the lifestyle for the better.
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