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You should be able to answer the following review questions from the material presented in this chapter. Radio-opaque substances are used in various ways to facilitate radiological examination of parts of the body.
They are used to treat severe acute asthma attacks and chronic asthma, in particular control of nocturnal asthma and early morning wheezing. Xanthines also have some use in chronic bronchitis.
In the skin, the drug combines with an intracellular vitamin D receptor to form a drug-receptor complex, which then binds to a specific sequence of DNA in the nucleus that modulates and controls transcription. As a result, the action of calcipotriol is to reduce proliferation and allow differentiation and maturation of keratinocytes.
Authored by Dr. Gregory Obara, MD