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Avoid abrupt withdrawal and rapid dose reduction after prolonged therapy. Volume of distribution: 0. Elimination half-life: Approx 2. Zolpidem uses include treatment of insomnia sleeplessness. Obstructive sleep apnoea, myasthenia gravis, compromised respiratory function. Distribution: Distributed into breast milk. Zolpidem is also used in other sleep disorders like frequent disturbances in sleep.
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Zolpidem is an imidazopyridine derivative that acts by binding to the benzodiazepine BZD receptors of the GABA receptor complex resulting in neuronal hyperpolarisation, action potential inhibition, increased in chloride conductance and decreased in neuronal excitability. Absorption: Rapidly absorbed from GI tract.
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