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Antabuse generic name: Disulfiram; brand name: Antabus is an aldehyde dehydrogenase inhibitor. Antabuse works by interfering with the way the body metabolises alcohol. Antabuse stops this enzyme from working. This means that when alcohol is consumed, the body cannot process it normally. Instead, acetaldehyde accumulates in the bloodstream, causing a variety of unpleasant effects e. This reaction to alcohol, known as the disulfiram reaction is usually enough to deter people from having another drink.

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It works by blocking an enzyme that breaks down alcohol in the body. This means that when people who are taking disulfiram drink alcohol, they develop a number of unpleasant symptoms known as the aldehyde reaction. Dosage and administration: Oral dosage for the maintenance treatment of alcohol dependence: initially, mg PO once daily every morning for 1 to 2 weeks, then reduce to mg PO once daily. The dose may be taken in the evening if drowsiness occurs. Recommended maintenance dosage range: mg to mg PO once daily. Required duration of treatment ranges from months to years, and is dependent on the patient's ability to abstain from ingesting alcohol. Antabuse Disulfiram mg effervescent tablets. Overdosage: High doses of disulfiram up to 6 g daily are relatively non-toxic in man. Antabuse is toxic to animals only in large doses. The LD50 of a single dose administration in the dog is 3.

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Addiction Treatment that Just Works Individualized treatment programs delivered in a comfortable, relaxed setting promote healing in your recovery journey. Disulfiram is a medication used to help people maintain sobriety. It is also known as Antabuse. It was discovered by a Danish researcher in Testing the drug on himself, he discovered that alcohol tasted terrible after taking the drug.

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