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Trials volume 17, Article number: Cite this article. Although overall population prevalence is low 0. We aim to recruit 88 participants: 28 unplanned inpatients and 60 planned outpatients. During detoxification we will compare baclofen 10 mg three times a day with placebo as an adjunct to the usual benzodiazepine regimen. In the planned outpatient arm, we will also compare a 2-day preload of baclofen 10 mg three times a day with placebo.

 

 

 

Gamma-hydroxybutyrate GHB withdrawal is a life-threatening condition that does not always respond to standard treatment with benzodiazepines. Here, we investigate current patterns of use and the online availably of baclofen. Data were collected according to pre-defined criteria. Gamma-hydroxybutyrate Baclofen price nhs is a naturally occurring metabolite of the neurotransmitter gamma-aminobutyric acid GABA and was first synthesised as an anaesthetic agent in 1. In addition, it has been used illicitly in both bodybuilding and as a recreational drug 3, 4. At low dose, stimulation of GHB receptors increases dopamine release resulting in stimulant-like effects, whilst at higher doses, binding to GABA-B receptors results in hypnotic effects and eventually coma 5.

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