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Archived from the original on 4 March Archived from the original on 18 January The New England Journal of Medicine. Sildenafil's popularity with young adults has increased over the years. Archived from the original on 26 September Our clinicians regularly offer patients the opportunity to take part in trials of new drugs and treatments. Sildenafil has been studied for high-altitude pulmonary edema, but its use is currently not recommended for that indication. Some complained of blurriness and loss of peripheral vision.

The substance is the same under both trade names. This is likely to lead to dramatic price reductions. Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus. Contraindications include: 4. D Y citrate: D Y. British Journal of Clinical Pharmacology. Journal of Toxicology and Environmental Health.

If taken with a high-fat meal, absorption is reduced; the time taken to reach the maximum plasma concentration increases by around one hour, and the maximum concentration itself is decreased by nearly one-third.

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