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On the other hand, to get appropriate blood levels, tadalafil may take up to two hours. Sildenafil citrate and vardenafil have a time frame of action in between 4 to 12 hours. On the other hand, tadalafil can affect a person for 24 and up to 36 hours. These common adverse effects of tadalafil are associated with the ability of PDE5 inhibition to cause the vessels to become wider.

They usually disappear quickly, not longer than after few hours. Back pain and muscle aches usually happen 12 to 24 hours after administering tadalafil. These would normally vanish after 48 hours. A brief guidance is required to ensure a patient understands the directions to use and realizes the potential risk the drug may cause.

We list only extreme cases. Since there came to be tadalafil marketed under the name of Cialis, the giant competitor of Viagra. It differs from the most famous blue pill for the duration of the effect that lasts up to 36 hours. It is estimated that in the U. It does not require any programming and has no constraints on food and alcohol intake. It would also offer a further choice of treatment, allowing the physician to locate the drug appropriate to the specific needs of each patient. While in the past products were used to stimulate erection, the future is represented by this new class of drugs: peripheral conditioners that do not cause erection, but facilitate the erection mechanism by acting not at the encephalic but peripheral level, i.

It is a drug of the same family of Viagra, it is a V phosphodiesterase inhibitor, that is, of that enzyme that blocks the release of the cavernous body during the erection phase. By blocking this enzyme, erectile mechanisms are facilitated. Additionally, while sildenafil should be strictly taken on an empty stomach and in the absence of alcohol, tadalafil has absorption kinetics so it is not affected by food or alcohol, to avoid difficulties and reduce absorption. All this gives couples more freedom in sexual intercourse programming.

Tadalafil side effects are very similar to those of sildenafil. A study was carried out at the Humanitas Clinical Institute, which involved 14 patients. Of these a group took the product 3 times a day in the morning, another only at the time of need. Having no action on the VI phosphodiesterase, which is present at the retina level, does not cause alteration of the color vision, so it can also be taken by people suffering from retinitis pigmentosa, a congenital eye disease for which sildenafil is contraindicated.

Tadalafil duration also beats that of vardenafil Levitra. Firstly, important diseases such as neuropathy or diabetes mellitus have to be excluded. Blood, urine and hormone dosage tests are sufficient to decide on the treatment that will be directed, first, to eliminating the modifiable factors such as smoking and alcohol.

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