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Dapoxetine, marketed as Priligy, among others, is a medication used for the treatment of premature ejaculation PE in men 18—64 years old. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast-acting property makes it suitable for the treatment of PE, but not as an antidepressant. Randomized, double-blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE. Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time IELT compared to that of dapoxetine 30 mg in men with lifelong PE, but no difference is seen in men with acquired PE.
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