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The research team sought to combat the use of ineffective medications, which is a growing problem in low-resource areas. Near-infrared NIR spectroscopy has emerged as a possible technique that could combat this problem. This approach was designed to offer a cost-effective and rapid alternative to traditional laboratory methods for drug quality assessment 1. The study initially validated quantitative PLSR models in Belgium, characterized by a temperate oceanic climate. Subsequently, the models were transferred to Cameroon, a tropical climate zone, where researchers encountered challenges in accurately predicting new validation series using the initial models 1. To overcome this hurdle, two augmentation strategies were devised to make the predictive models more robust against environmental factors. These strategies incorporated the potential variability linked to environmental effects in the initial calibration sets 1. The resulting models were then put to the test during in-field analysis of ciprofloxacin and metronidazole tablet samples collected from three different cities in Cameroon. The utilization of low-cost handheld NIR spectrophotometers, coupled with robust calibration models, could significantly improve the efficiency and accuracy of drug quality assessment, ultimately safeguarding public health 1. This article was written with the help of artificial intelligence and has been edited to ensure accuracy and clarity.
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Ciprofloxacin ophthalmic solution is used to treat bacterial infections of the eye including conjunctivitis pinkeye; infection of the membrane that covers the outside of the eyeball and the inside of the eyelid and corneal ulcers infection and loss of tissue in the clear front part of the eye. Ciprofloxacin ophthalmic ointment is used to treat conjunctivitis. It works by liquid ciprofloxacin cost the bacteria that cause infection. Ophthalmic ciprofloxacin comes as a solution liquid and an ointment to apply to the eyes. Ciprofloxacin ophthalmic solution is usually used often, between once every 15 minutes to once every 4 hours while awake for 7 to 14 days or longer. Ciprofloxacin ophthalmic ointment is usually applied 3 times a day for 2 days and then twice a day for 5 days.
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