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Ciprofloxacin is used for the treatment of disseminated gonococcal infection, A but is not licensed for this indication. Ciprofloxacin is used for the treatment of uncomplicated gonorrhoea, A but is not licensed for this indication. Licensed for use in children over 1 year for complicated urinary-tract infections, for pseudomonal lower respiratory-tract infections in cystic fibrosis, for prophylaxis and treatment of inhalational anthrax. Licensed for use in children over 1 year for other infections where the benefit is considered to outweigh the potential risks. The CSM has warned that quinolones may induce convulsions in patients with or without a history of convulsions; taking NSAIDs at the same time may also induce them. Healthcare professionals are reminded that

The pharmacokinetics of ciprofloxacin Bay o was examined after a single oral dose of mg and a single intravenous dose of mg respectively in six healthy male volunteers in an open, randomized crossover study. Although ciprofloxacin concentrations were measured in serum, plasma and urine by HPLC cipro order fluorimetric detection and by microbiological assay, all pharmacokinetic calculations are based on the highly sensitive HPLC method only. The mean serum concentration of ciprofloxacin peaked approximately 1 h after the oral dose 0. The elimination half-life was about 4 h and the renal clearance was 4. The volume of distribution of the central compartment was calculated to be 0.

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