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Initial daily dose not to exceed 1. Doses up to 2 mg once daily have been used in clinical trials Montagna ; Peled ; Saletu Additional data may be necessary to further define the role of clonazepam in the treatment of this condition. Clonazepam metabolites may accumulate in patients with renal impairment.
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One-half of these patients received clonazepam, 0. Analysis of variance confirmed a significant effect of clonazepam for average Hamilton depression scores. No serious adverse events were found in either treatment group. Taper effects appeared modest and transitory. Conclusions: Clonazepam augmentation of fluoxetine was superior to fluoxetine alone in the first 3 weeks of treatment.
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