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That medication should be swallowed whole. It should not be used, crushed or chewed. This medication may irritate the treatment, and should be taken with water. It is best to avoid coffee, spicy food or chemical. Each person may allow differently to a stimulant. If you think this treatment may be causing side effects including those distorted here, or others, extend to your health care professional.

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Use: For the treatment of signs and symptoms of osteoarthritis in patients at high risk of developing nonsteroidal anti-inflammatory drug NSAID induced gastric and duodenal ulcers and their complications. Use: For the treatment of signs and symptoms of rheumatoid arthritis in patients at high risk of developing NSAID induced gastric and duodenal ulcers and their complications. Use with caution in patients with advanced renal disease; if treatment is initiated, close monitoring of renal function is recommended. This drug should be used at the lowest effective dose in order to achieve therapeutic efficacy and minimize adverse effects; however, this fixed combination product is not recommended for patients who would not receive the appropriate dose of both ingredients.