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Skin rashes, which are the only sign of Kirle's disease, can be located on various parts of the body, so it is not necessary to talk about the typical localization of the pathological process. Distinctive features of changes in this pathology are: the appearance of the first signs in the armpits. It cannot be said that Kirle's disease has any peculiarities when localized on the face, however, changes are quite often found on the scalp and face, they are a great aesthetic disadvantage and cause psychological suffering. Since rashes are the only manifestation of the disease, and there are no subjective sensations, patients often seek help precisely when changes are localized on the face or other open areas of the body. Among the factors that can contribute to the appearance of the disease, it is worth mentioning: hereditary predisposition the disease is more often observed in children whose parents suffered from such a pathology ; hormonal disorders diabetes mellitus, impaired glucose tolerance ; liver damage hepatitis of various nature, hepatosis ; diabetic nephropathy; a certain role is given to a lack of vitamin A it can also be the cause of the development of leukoplakia on the mucous membranes and atrophic changes in the skin.
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These drugs prevent infection of red blood cells. Treatment should begin one or two weeks before travelling to areas where malaria is endemic and be continued for at least four weeks after returning. No form of malaria prophylaxis is completely effective and other precautions should be taken. However, should an infection occur the symptoms are usually less severe.
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Authored by Anthony P Moreno, MD