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Doxycycline is used to treat bacterial infections in many different parts of the body. It is also used to treat pimples and abscesses usually on the face that are caused by rosacea, also known as acne rosacea or adult acne. Doxycycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth.

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A US study that provided gay and bisexual men and transgender women with the antibiotic doxycycline to take after condomless sex was stopped a year early because of its high efficacy, the 24th International AIDS Conference in Montreal was told yesterday. The DoxyPEP study examined the incidence of gonorrhoea, chlamydia and syphilis in people. Two-thirds of them were given doxycycline to take after sex while one-third were not provided with the drug. The study was originally going to end in May but was stopped a year early last May. At the time the researchers made it clear that the study was stopped because of positive findings, but the exact data were not released until today.

It is an inexpensive broad-spectrum antimicrobial agent largely used in the management of several bacterial infections, particularly involving intracellular pathogens, as well as in the treatment of acne or for the prophylaxis of malaria. Physicochemical characteristics of doxycycline liposolubility allow a high diffusion in the tissues and organs. It has high bioavailability and a long elimination half-life allowing oral administration of one or two daily doses. More recently, indications for doxycycline in STI prophylaxis have been evaluated. Its liposolubility confers excellent bioavailability and high tissue and fluid penetration.

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