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Lunesta, also known as eszopiclone, was approved by the FDA in December, for the short-term treatment of insomnia 1. Moreover, Lunesta is indicated for use in patients suffering from insomnia, above the age of 18 1. Lunesta, also known as eszopiclone, is a non-benzodiazepine hypnotic agent, with a molecular weight of Once taken, Lunesta eszopiclone is rapidly absorbed from the gastrointestinal GI tract within one hour 3. Peak plasma concentrations of Lunesta are reached after around 1 hour of oral administration, and is binds weakly to plasma protein 4.

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Eszopiclone Lunesta, a nonbenzodiazepine hypnotic agent, is indicated for the treatment of transient and chronic insomnia. The duration of action of eszopiclone is approximately eight hours, similar to zolpidem Ambien and longer than zaleplon Sonata. The drug is metabolized in the liver by the CYP 3A4 system, and dose adjustment is warranted in patients taking enzyme inhibitors such as ketoconazole Nizoral. Eszopiclone is a Schedule IV controlled substance. After one week of therapy, eszopiclone-treated patients fell asleep a mean of 37 minutes faster, had 0.

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