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This medication is used along with a diet and exercise program. The maximum daily dose should not exceed mg a day. It may come from other suppliers around the world.

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See Prescribing in renal impairment. Determine renal function before treatment and at least annually at least twice a year in patients with additional risk factors for renal impairment, or if deterioration suspected. Child 10—17 years specialist use only Initially mg once daily, dose to be adjusted according to response at intervals of at least 1 week, maximum daily dose to be given in 2—3 divided doses; maximum 2 g per day.

Adult Initially mg once daily for at least 1 week, dose to be taken with breakfast, then mg twice daily for at least 1 week, dose to be taken with breakfast and evening meal, then mg 3 times a day, dose to be taken with breakfast, lunch and evening meal; maximum 2 g per day. Adult Initially mg once daily, then increased if necessary up to 2 g once daily, dose increased gradually, every 10—15 days, dose to be taken with evening meal, alternatively increased to 1 g twice daily, dose to be taken with meals, alternative dose only to be used if control not achieved with once daily dose regimen.

If control still not achieved then change to standard release tablets. Adult initiated by a specialist Initially mg once daily for 1 week, dose to be taken with breakfast, then mg twice daily for 1 week, dose to be taken with breakfast and evening meal, then 1. Dose adjustments In children: Manufacturer advises consider dose reduction in moderate impairment.

In adults: Manufacturer advises reduce dose in moderate impairment—consult product literature. Funding decision: Recommended with restrictions. In a week study, the Mounjaro 5-mg, mg, and mg doses were compared to placebo in adults with type 2 diabetes who were also taking insulin glargine. They had a starting A1C of 8.

Low blood sugar hypoglycemia. Your risk for getting low blood sugar may be higher if you use Mounjaro with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, or mood changes, hunger, weakness, and feeling jittery.

For people taking Mounjaro and insulin glargine, their A1C was lowered by 2. For people taking placebo and insulin glargine, their A1C was lowered by 0. Kidney problems kidney failure. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids dehydration, which may cause kidney problems to get worse.

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