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Recommended Dose: One 25 mg tablet once daily after a meal 2. Patients with a known hypersensitivity to the drug or to any of the excipients 4. AROMASIN is indicated for adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to AROMASIN for completion of a total of five consecutive years of adjuvant hormonal therapy see Clinical Studies Each tablet contains 25 mg of exemestane. Reductions in bone mineral density BMD over time are seen with exemestane use. Table 1 describes changes in BMD from baseline to 24 months in patients receiving exemestane compared to patients receiving tamoxifen IES or placebo Concomitant use of bisphosphonates, vitamin D supplementation, and calcium was not allowed. Monitor patients for bone mineral density loss and treat as appropriate. Women with vitamin D deficiency should receive supplementation with vitamin D.

 

 

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