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It has a short acting therapeutic effect so treatment should be reserved for those daily activities and times when relief from these symptoms of multiple sclerosis MS is most important.
Structurally, tizanidine is similar to clonidine, but only to as potent for lowering blood pressure. Elliott, in Current Therapy in Pain, Tizanidine had been used predominantly in the management of spasticity; however, it has also proved useful for a variety of painful conditions. As to its efficacy in the management of spasticity, tizanidine compares favorably with both baclofen and and seems to cause less muscle weakness than baclofen and a lower incidence of sedation than. It appears that muscle strength is fairly well preserved in patients taking tizanidine for spasticity or muscle spasm, because less weakness is associated with use of this drug compared with baclofen or.
Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. Tizanidine was approved for medical use in the United States in Tizanidine has been found to be as effective as other antispasmodic drugs and is more tolerable than baclofen and diazepam. Side effects include dizziness, drowsiness, weakness, nervousness, confusion, hallucinations, strange dreams, depression, vomiting, dry mouth, constipation, diarrhea, stomach pain, heartburn, increased muscle spasms, back pain, rash, sweating, and a tingling sensation in the arms, legs, hands, and feet. Tizanidine has drug abuse potential. It has been recognized to cause dependence and addiction. Concomitant use of tizanidine and moderate or potent CYP1A2 inhibitors such as zileuton, certain antiarrhythmics amiodarone, mexiletine, propafenone, verapamil, cimetidine, famotidine, aciclovir, ticlopidine and oral contraceptives is contraindicated. Concomitant use of tizanidine with fluvoxamine, a potent CYP1A2 inhibitor in humans, resulted in a fold increase in the tizanidine AUC plasma drug concentration-time curve. Fluoroquinolone antibiotics such as moxifloxacin, levofloxacin, and ciprofloxacin should also be avoided due to an increased serum concentration of tizanidine when administered concomitantly. Alcohol should be avoided, particularly as it can upset the stomach.
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It's used to treat muscle spasms caused by certain conditions such as multiple sclerosis, ALS, or spinal cord injury. It is also prescribed off-label for certain headache disorders, symptoms of fibromyalgia, and as a sleep aid. Tizanidine works by blocking nerve impulses that are sent to your brain. If you are suffering from spasms, cramping, and tightness of the muscles, your doctor may prescribe tizanidine. Tizanidine is a short-acting medication that you should only take for daily activities that require relief from muscle spasms. Tell your doctor if you have any type of previous injury to your liver.
This medication is a muscle relaxant. It may also have other uses. Its effects can be noticed within a few hours. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Generally, it is used only as needed. Do not use more of this product, or more often, than prescribed.
These health issues are also linked to symptoms like muscle rigidity and hypertonia. In these cases, tizanidine hydrochloride is used as a muscle relaxant to mitigate pain. Since it alleviates pain, is tizanidine a narcotic? While narcotics are substances traditionally used to treat pain by binding to receptors in the nervous system — such as opioids - tizanidine is a muscle relaxer. In other words, Zanaflex slows down communication in the brain and nervous system to relax the muscles and alleviate tension, spasms, and pain. For this reason, Zanaflex aids in alleviating symptoms of multiple sclerosis MS, a disease that affects nerve function and contributes to loss of muscle coordination, weakness, vision problems, bladder control, and stroke.
When you first start taking tizanidine, your doctor will give you a small dose. Your dose will then be increased at 3- to 4-day intervals until you are on a dose that suits your condition. Tizanidine can make you feel sleepy or dizzy. It can slow your reactions, so please take care if you are using tools or machines, or if you drive. Continue to take the tablets unless your doctor tells you otherwise. Do not suddenly stop taking tizanidine tablets.
Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury 9. It may also be caused by musculoskeletal injury 5.
Your medication may look different. If you have questions, ask your pharmacist.
It is used to treat muscle spasms or muscle spasticity causing symptoms such as muscle pain, stiffness, and muscle tightness. Tizanidine is often prescribed to relieve the increased muscle tone and muscle spasms in people with muscle spasticity, multiple sclerosis, and spinal cord injury.
Tizanidine is used alone or in conjunction with other standard therapies e. In these patients, tizanidine decreases the number and severity of spasms, alleviates clonus, and improves mobility to a greater extent than does placebo. Some evidence from comparative studies suggests that tizanidine may produce muscle weakness less frequently than other antispastic agents e. The manufacturer states that because of its short duration of effect, tizanidine should be lisinopril 40 mg price for those daily activities and times when relief of spasticity is most important. Efficacy for the management of spasticity has been demonstrated in 2 placebo-controlled, randomized studies in patients with multiple sclerosis or spinal cord injury. In these studies, patients years of age received initial tizanidine hydrochloride dosages of 2 or 4 mg daily, which were titrated according to response and tolerance to a maximum of 36 mg in up to 3 divided doses daily over a 3-week period.
It should always be taken consistently zanaflex 4 mg tablet food or without food, though. Common side effects of Zanaflex include dry mouth, weakness, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how Zanaflex affects you. This medication may be prescribed for other uses. This is not a complete list of Zanaflex side effects. Especially tell your doctor if you take