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Give in two equally divided doses. Discontinue if anaphylaxis or angioedema occurs; do not rechallenge. Suicidal order trileptal and ideation monitor. Monitor for seizures during pregnancy and through the postpartum period. Monitor plasma levels of other AEDs esp. May decrease effectiveness of hormonal contraceptives containing ethinyl-estradiol or levonorgestrel; use additional or alternative non-hormonal methods.

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Replacement for other antiepileptic drugs when current therapy provides insufficient seizure control see Pharmacology: Pharmacodynamics: Clinical Studies under Actions. Contraindications: Known hypersensitivity to oxcarbazepine or to any of the excipients. If a patient develops these reactions after treatment, the drug should be discontinued and an alternative treatment started. Hypersensitivity reactions, including multi-organ order trileptal reactions, may also occur in patients without history of hypersensitivity to carbamazepine. Such reactions can affect the skin, liver, blood and lymphatic system or other organs, either individually or together in the context of a systemic reaction see Adverse Reactions.

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Monitoring serum concentration during oxcarbazepine therapy. Assessing potential toxicity. Collect specimen immediately before next scheduled dose. Centrifuge and order trileptal serum into plastic vial within 2 hours of collection. Oxcarbazepine OCBZ is approved as monotherapy and adjunctive therapy for partial seizures with and without secondary generalized seizures in adults and as adjunctive therapy for partial seizures in children. In humans, OCBZ is a prodrug that is almost immediately and completely metabolized to hydroxy,dihydrocarbamazepine, known as monohydroxy carbamazepine MHDC, an active metabolite that is responsible for OCBZ's therapeutic effect.

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