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The chemical designation is 3-ethyl-6,7,8,9-tetrahydromethyl-4H-pyridopyrimidinone. Efficacy was established in 4 short-term trials in adults, 2 short-term trials in adolescents ages 13 to 17 years, and one long-term maintenance trial in adults. Efficacy was established in 2 short-term trials in adults and one short-term trial in children and adolescents ages 10 to 17 years. Efficacy was established in one short-term trial in adults. Efficacy was established in 3 short-term trials in children and adolescents ages 5 to 17 years. Severe Renal and Hepatic Impairment in Adults: use a lower starting dose of 0.

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