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Meet your Best of the Best Pharmacy Award winners! Steroid medications are used in a wide variety of emergency medical situations as well as for many other acute and chronic inflammatory conditions and disease states. Both drugs are corticosteroids, also known as glucocorticoids or steroids. They are used for a wide variety of inflammatory conditions in many organ systems. Although dexamethasone and prednisone are both steroids, they have some differences, which we will describe below.

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Dexamethasone is a fast-acting glucocorticoid corticosteroid. Glucocorticoids have effect on virtually every cell type and body system. Although glucocorticoids have been used to treat many conditions in humans and animals, dexamethasone has five primary uses with accompanying dosage ranges: 1 as a diagnostic agent to test for hyperadrenocorticism, 2 as a replacement or supplementation for glucocorticoid deficiency secondary to hypoadrenocorticism, 3 as an anti-inflammatory agent, 4 for immunosuppression, and 5 as an antineoplastic agent.

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Anovulation is one of the more common causes of infertility. Dexamethasone is one such option. This is a medicine that makes Clomid more effective for ovulation. It acts on the adrenal glands to decrease their production of androgens, hormones that interfere with egg growth and development.

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Corticosteroids were first used in clinical practice in for the treatment of rheumatoid arthritis. Indications since then have spanned multiple specialties and organ systems, including dermatology, rheumatology, immunology and oncology. If physicians understand the composition and physiologic effects of corticosteroid agents, appropriate drug selection can be made and inappropriate or problematic uses can be avoided. Corticosteroid agents mimic the endogenous steroid hormones produced in the adrenal cortex—mineralocorticoid aldosterone and glucocorticoid cortisol.

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One hundred and thirty consecutive cases were enrolled. A risk stratification tool was developed to select candidates for corticosteroid switch based on the independent prognostic predictors of PFS and OS. Metastatic castration-resistant prostate cancer mCRPC is one of the leading causes of death among men worldwide 1.

In the study, the drug reduced the number of deaths by one-third for people on ventilators, and by one-fifth for people on oxygen. The dexamethasone tablet is available as the brand-name drugs DexPak and Decadron. A class of drugs is a group of medications that work in a similar way.

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