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Many patients at high risk of cardiovascular disease do not achieve recommended low-density lipoprotein cholesterol LDL-C goals. This study compared the efficacy and safety of low doses of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia. The primary endpoint was the percentage change from baseline in LDL-C levels at 6 weeks. Rosuvastatin 10 mg reduced LDL-C levels significantly more than atorvastatin 20 mg at week 6 High-density lipoprotein cholesterol was increased significantly with rosuvastatin 10 mg versus atorvastatin 20 mg 6. The use of rosuvastatin 10 mg was also cost-effective compared with atorvastatin 20 mg in both a US and a UK setting.
The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. How long does it take for this medicine to take effect? The peak effect of this medicine can be observed within 3 to 5 hours of administration of the dose. How long do the effects of this medicine last? Is it safe to consume alcohol while taking this medicine? Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption. Can this medicine be taken during pregnancy? This medicine is not recommended for use in pregnant women.
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