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The effectiveness of amitriptyline, carbamazepine, gabapentin, and for the treatment of neuropathic pain has been demonstrated, but it is unknown which one is the most cost-effective. We designed a cost-utility analysis of a hypothetical cohort with neuropathic pain of postherpetic or diabetic origin.
Background: Painful diabetic neuropathy is common and adversely affects patients' quality of life and function. Several treatment options exist, but their relative efficacy and value are unknown. Objective: To determine the relative efficacy, costs and cost effectiveness of the first-line treatment options for painful diabetic neuropathy.
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Authored by Martin Maag, MD