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Triptans are a group of drugs targeted at alleviating symptoms of migraine, a severe and often debilitating maxalt cost australia that can affect sight and speech. Triptans are derived from the amino acid tryptophan and designed to resemble the serotonin molecule and mimic its effects on subgroups of serotonin receptors in the brain. The triptans available in Australia are: sumatriptan Imigran and other brands, zolmitriptan Zomig, naratriptan Naramig, rizatriptan Maxalt and eletriptan Relpax. The making of the triptan class of drugs is a case study in rational drug development. Early research in the s suggested the anti-migraine effect of known drugs such as ergotamine was due to them causing constriction of certain blood vessels in the brain, known as vasoconstriction. Further work established that several subgroups of receptors, activated by the common neurotransmitter serotonin, appeared protective against migraine.

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