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However, most research on the buy h57 hoodia drug to date has focused on patients of European ancestry, in which nearly 30 percent have been found to carry a genetic mutation that makes it difficult to metabolize the drug, Magavern said. The prevalence of these loss-of-function mutations in other populations, such as South Asians, has been understudied. South Asians are a growing demographic in the UK, especially in central and east London, Magavern said. As of, the most recent UK census, about 7 percent of the population in England and Wales was Bangladeshi, Indian, or Pakistani, compared to 5 percent the decade prior. They found that 57 percent of the more than 44, participants were likely intermediate or poor CYP2C19 metabolizers with at least one loss-of-function allele.

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