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Although the well-known antibiotic norfloxacin NOR is recognized as an important environmental pollutant, little is known about its impacts on ecological processes, particularly on species interactions. In h-long lethal experiment, mortality rates of D. In sublethal experiments, heartbeat rate decreased, while time ratio of vertical to horizontal swimming TVH and the duration of quiescence increased in D. These collectively led to decreases in both average swimming ability and feeding rate, consistent with the positive relationship between average swimming ability and feeding rate. Overall, results indicate that, by affecting zooplankton heartbeat rate and behavior, NOR decreased feeding efficiency of D. Over the past decades, antibiotics have been widely used for both human and veterinary therapy. In China, the annual production of antibiotics exceeds, tons 1, leading to an increased possibility of these antibiotics being released into aquatic environments.
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Norfloxacin, a poorly absorbed fluoroquinolone, has been used to achieve selective intestinal decontamination in cirrhotic patients; norfloxacin has several characteristics that make it suitable for prophylaxis. Sparing of gram-positive and anaerobic organisms to maintain their protective role in the normal gut flora a. Norfloxacin reduces the frequency of SBP, delays progression to hepatorenal syndrome, and improves overall survival. Norfloxacin prophylaxis is cost effective in reducing recurrent SBP. However, norfloxacin treatment does not alter the overall mortality in these patients. Norfloxacin has not been available in the United States since
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