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Collaboration with industry, lawmakers, and patient advocacy organizations has been essential to improving marketing practices and competitiveness in generic manufacturing. Still, we continue to face challenges particular to the generic drug landscape. Some of these arise from the scientific and regulatory complexities essential to the products themselves, whereas others appear to stem from societal perceptions of drug development and regulation that we are still working to appreciate. In the absence of such evidence, the ATA recommended that prescribers avoid switching between levothyroxine products in the treatment of hypothyroid patients. As a result of that recommendation, brand-name levothyroxine was preferentially prescribed over generic levothyroxine products. These results establish evidence that should mitigate concerns such as those raised by the ATA over levothyroxine product switching.

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