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Dutasteride prevents testosterone from converting to dihydrotestosterone DHT in the body. Dutasteride and tamsulosin is a combination medicine used to treat benign prostatic hyperplasia BPH in men with an enlarged prostate.
In men with benign prostatic hyperplasia, is treatment with a combination of dutasteride and Tamsulosin more effective than with either drug given as a monotherapy in reducing the time to acute urinary retention or surgical treatment of BPH? Combination therapy provides better symptom relief than either medication provided as a monotherapy, at four years. First line treatment is by medical management with 5-aplha reductase inhibitors 5-ARIs and alpha blockers being among the choices available. This study investigates if a combination of these two drug classes Dutasteride and Tamsulosin provides better outcomes for patients when compared with either drug given as a monotherapy. Combination therapy was effective in secondary outcomes such as BPH clinical progression, IPSS health status, urinary flow rates and prostate volume reduction.
Dutasteride is used alone or with another medication tamsulosin Flomax to treat benign prostatic hyperplasia BPH; enlargement of the prostate gland. Dutasteride is used to treat symptoms of BPH and may reduce the chance of developing acute urinary retention sudden inability to urinate. Dutasteride may also decrease the chance that prostate surgery will be needed. It works by blocking the production of a natural substance that enlarges the prostate. Dutasteride comes as a capsule to take by mouth. It is usually taken once a day with or without food. Take dutasteride at around the same time every day. Take dutasteride exactly as directed.
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Each capsule contains combination of Dutasteride USP 0. Dutasteride is a synthetic 4-azasteroid compound which inhibits the androgen primarily responsible for the initial development and subsequent enlargement of the prostate gland. Smooth muscle tone is mediated by the sympathetic nervous stimulation of alpha1-adrenoceptors, which are abundant in the prostate, prostatic capsule, prostatic urethra, and bladder neck. Blockade of these adrenoceptors can cause smooth muscles in the bladder neck and prostate to relax, resulting in an improvement in urine flow rate and a reduction in symptoms of BPH. Tamsulosin, an alpha1-adrenoceptor blocking agent, exhibits cheap aciphex online for alpha1-receptors in the human prostate.
Avodart helps improve urinary flow and may also reduce the need for prostate surgery later. Tell your doctor all medications you use. Avodart is not usually used in women. Therefore, it is unlikely to be used during pregnancy or breastfeeding. Consult your doctor if you have questions. The sexual side effects of dutasteride may avodart 0.4 mg after you stop taking this medicine.
Each capsule contains lecithin which may contain soya oil. For the full list of excipients, see section 6. The capsules may be taken with or without food. Although an improvement may be observed avodart 0.4 mg an early stage, it can take up to 6 months before a response to the treatment can be achieved. No dose adjustment is necessary in the elderly.
Dutasteride — tamsulosin is a combination medication that is used to treat moderate-to-severe symptoms of benign prostatic hyperplasia BPH. BPH is a avodart 0.4 mg enlargement of the prostate gland that usually occurs in men after the age of Dutasteride belongs to a class of medications known as 5-alpha-reductase inhibitors. It works to reduce the production of dihydrotestosterone DHT, a hormone that causes enlargement of the prostate gland. Dutasteride relieves symptoms of BPH by reducing the size of the prostate and improving the flow of urine. Tamsulosin belongs to a group of medications known as alpha 1A receptor antagonists.
Use of the 5-alpha reductase inhibitor 5-ARI was also associated with several parameters of metabolic dysfunction, including increased glucose and hemoglobin A1c and cheap aciphex online abnormalities. Most importantly, this agent worsens sexual function and reduces quality of life. Using a registry from a single urology office, Dr Traish and colleagues compared data from men aged 47 to 68 taking dutasteride 0. However, the 5-ARI also was associated with increased blood glucose, hemoglobin A1c, triglycerides, and low-density lipoprotein levels over the long term. In addition, dutasteride appeared to increase liver transaminase activity and Aging Male Symptom score, which indicates inflammation and reduced quality of life. The team also found reduced testosterone levels and worsening ED as assessed by the International Index of Erectile Function questionnaire.
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