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All FDA black box warnings are at the end of this fact sheet. Bupropion is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder MDD, seasonal affective buy generic lamictal online SAD, and to help people quit smoking smoking cessation. SAD is a type of depression that occurs mainly during the autumn-winter season. They should be clear about the limits of the research around that medication and if there are any other options.

 

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The process known as first pass metabolism is drastically reduced with ageing. Drugs that would normally undergo this process, achieve far higher blood levels in older patients than would otherwise be expected. This is of particular significance in drugs administered orally and the oral dosage of such drugs must be reduced in older people. Older patients appear to be more at risk of developing drug-induced hepatitis particularly with the use of non-steroidal anti-inflammatory drugs. The principal organ of excretion for the majority of drugs is the kidney.

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