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Quetiapine is an atypical antipsychotic approved for the treatment of patients with psychotic disorders. Symptoms associated with intoxication were coma without arterial hypotension, persistent tachycardia, hyperglycemia, and transient hypothyreoidism. Management consisted of intubation for airway protection, gastric lavage, the use of activated charcoal, i. Despite the extremely high dose of quetiapine, the patient recovered completely without residual symptoms. Quetiapine is indicated and approved for the treatment of psychotic disorders in adults by the U. After oral administration the drug is eliminated with a mean terminal half-life of approximately 7 hours. The drug exhibits high affinity for serotonergic 5-H -receptors and moderate affinity for dopamine D 2 -receptors; whereas antagonism of D 1 - and 5-H -receptors is relatively weak.

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Seroquel can be used to treat several illnesses, such as Weight gain has been seen in patients taking Seroquel. You and your doctor should check your weight regularly. If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby ask your doctor for advice before taking this medicine. You should not take Seroquel during pregnancy unless this has been discussed with your doctor. Seroquel should not be taken if you are breast-feeding. Your tablets may make you feel sleepy.

Common side effects include sleepiness, constipation, weight gain, and dry mouth. In those with bipolar disorder, quetiapine is used to treat depressive episodes; acute manic episodes associated with bipolar I disorder as either monotherapy or adjunct therapy to lithium ; valproate or lamotrigine ; and maintenance treatment of bipolar I disorder as adjunct therapy to lithium or divalproex. Quetiapine is effective when used by itself and when used along with other medications in major depressive disorder MDD. It is sometimes used off-label, often as an augmentation agent, to treat conditions such as Tourette syndrome, musical hallucinations and anxiety disorders. Owing to the risks associated with clozapine e. Sources for incidence lists

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Quetiapine belongs to a class of medications known as antipsychotics. It is used to treat symptoms of schizophrenia, manic episodes associated with bipolar disorder, and depressive episodes associated with bipolar disorder. It works by affecting the actions of certain chemicals in the brain known as neurotransmitters. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

At low doses 25mg, quetiapine is a histamine-1 receptor and alpha-1 adrenergic antagonist. At doses between 50—mg, it increasingly antagonises serotonin receptors, and at higher doses above mg it antagonises dopamine-2 receptors. The higher doses acting on the serotonergic and dopaminergic receptors provide the antidepressant and antipsychotic effects respectively. To aid the understanding of quetiapine prescribing in general practice, a retrospective audit of the prescribing of quetiapine in 57 practices in the Compass Health Primary Health Organisation PHO was undertaken. This was in response to a concern by the Clinical Quality Board of Compass Health that quetiapine was being prescribed off label.

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Quetiapine belongs to a class of medications known as antipsychotics. How should I use this medication? Who should NOT take this medication? What side effects are possible with this medication? Are there any other precautions or warnings for this medication?

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Standard quetiapine tablets come in strengths of 25mg, mg, claritin loratadine 5mg, mg and mg. The slow release tablets come in strengths of 50mg, mg, mg, mg, mg and mg. Your doctor may ask you to change your dose, depending on how well quetiapine works for you. It can take a few weeks to get to the dose that works best for you. You'll usually start on a low dose of 50mg a day when taking standard tablets. This will be increased over a few days to start with.

Government of Newfoundland and Labrador. Strength This refers to the amount of the active medicinal ingredient e.