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Theophylline ER Extended-release is a bronchodilator used to open air passages in the lungs. Always check the medicine when it is refilled to make sure you are getting the correct brand and type as prescribed by your veterinarian. Ask the pharmacist if you have any questions about the medication you received from the pharmacy. There are many medications that can interact with theophylline. These include vitamins, minerals, herbal products, and medications prescribed by other veterinarians.

Theophylline is used to treat or prevent the symptoms of bronchial asthma, chronic bronchitis, emphysema, and other diseases involving constriction of the airways. Theophylline helps to ease the cough, wheezing, shortness of breath, and troubled breathing associated with these conditions by allowing relaxation of the tubes bronchi of the airways, thereby permitting increased amounts of air to flow through them. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

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In vitro, a perfect zero-order release rate with the osmotic order theophylline was obtained. In all subjects, application of the osmotic system resulted in a constant steady-state theophylline level just as in a long time zero-order i. The in vivo and in vitro release rates were almost identical and subjectindependent. Rent this article via DeepDyve. Controlled Release Pharmaceuticals. American Pharmaceutical Association, Washington, D.

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The objective of this work was to use theophylline as a model drug and to predict its pharmacokinetics before, during including prediction of the umbilical cord order theophylline, and after pregnancy as well as in milk after single and multiple doses and in neonates using a physiological-based pharmacokinetic PBPK model. Neonatal theophylline exposure from milk consumption was projected in both normal term and preterm subjects. Predicted infant daily doses were calculated using theophylline average and maximum concentration in the milk as well as an estimate of milk consumption. Predicted concentrations and parameters from the PBPK model were compared to the observed data. The PBPK model predicted an average cord-to-maternal plasma ratio of 1.

Theophylline is used in the treatment of reversible airway obstruction due to chronic asthma, chronic bronchitis, or COPD. Theophylline is well absorbed when taken orally as a rapid-release tablet or when administered as a liquid solution. Theophylline distributes rapidly into fat-free tissues and body water. Theophylline passes freely across the placenta, into breast milk and into cerebrospinal fluid. Theophylline is primarily eliminated by hepatic metabolism involving isoenzymes of the cytochrome Cost of skelaxin 800 mg system. Age and disease are the major endogenous factors influencing metabolism: clearance is markedly reduced in the neonates and elderly and increased in the first decade of life.

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Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. The main actions of theophylline involve: 2. The main therapeutic uses of theophylline are for treating: 2. It can also order theophylline nausea, diarrhea, increase in heart rate, abnormal heart rhythms, and CNS excitation headaches, insomnia, irritability, dizziness and lightheadedness. Its toxicity is increased by erythromycin, cimetidine, and fluoroquinolones, such as ciprofloxacin. In addition to seizures, tachyarrhythmias are a major concern.

In addition to giving you a boost of energy, caffeine may lower your risk of certain conditions. But consuming too much can lead to less desirable effects like headaches, confusion, and high blood pressure. Many of us rely on a morning cup of coffee or a jolt of caffeine in the afternoon to help us get through the day. Caffeine is so widely available that the U. But caffeine does so much more than just keeping you awake.

Aminophylline Injection, USP is a sterile, nonpyrogenic solution of aminophylline in water for injection. Aminophylline Injection is administered by slow intravenous injection or diluted and administered by intravenous order theophylline. When smaller doses are required the unused portion should be discarded. Aminophylline is a complex of theophylline and ethylenediamine. Theophylline is structurally classified as a methylxanthine. Aminophylline occurs as a white or slightly yellowish granule or powder, with a slight ammoniacal odor.