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People who take nonsteroidal anti-inflammatory drugs NSAIDs other than aspirin such as indomethacin may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. Do not take an NSAID such as indomethacin if you have recently had a heart attack, unless directed to do so by your doctor. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. If you will be undergoing a coronary artery bypass graft CABG; a type of heart surgery, you should not take indomethacin right before or right after the surgery.

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