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Duloxetine, sold under the brand name Cymbalta among others, 1 is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Duloxetine is a serotonin—norepinephrine reuptake inhibitor SNRI. Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States and in the European Union in The main uses of duloxetine are in major depressive disorder, generalized anxiety disorder, neuropathic pain, chronic musculoskeletal pain, and fibromyalgia.

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Duloxetine Cymbalta is a serotonin and norepinephrine reuptake inhibitor in the same class as venlafaxine Effexor. Food and Drug Administration FDA for use in the treatment of major depressive disorder and of diabetic peripheral neuropathic pain. In Europe it is marketed for the treatment of stress urinary incontinence; it is not approved for that indication in the United States. Duloxetine is considered to be safe. In one open-label study 1 there were seven suicide attempts among 1, patients in one year one suicide attempt per patient-years of drug exposure and no cases of fatal acute overdose. Duloxetine should not be used in patients taking a monoamine oxidase inhibitor MAOI, including a period of five days before initiation of the MAOI and 14 days after its discontinuation. Duloxetine plasma concentrations may be increased significantly by some antidepressants, quinidine, and quinolone antibiotics. Duloxetine may increase the plasma concentrations of other antidepressants, antipsychotics, and type 1C antiarrhythmics such as propafenone Rythmol and flecainide Tambocor. Serum alanine transaminase levels increased to more than three times the upper limit of normal in about 1 percent of patients taking duloxetine in placebo-controlled trials 2 ; alcohol may increase this risk. Duloxetine is not recommended in patients with end-stage renal disease or severe renal impairment because of the increased plasma concentrations of the drug and its metabolites.

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In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts for at least six months, pain from diabetic nerve damage, fibromyalgia, and long-term muscle or bone pain. It works by increasing the levels of the neurotransmitters serotonin and norepinephrine, which help regulate mood and may block pain signals traveling through the brain. The researchers noted that use of Cymbalta could result in fewer side effects than the drugs traditionally used for the condition, such as non-steroidal anti-inflammatory drugs, or NSAIDs, which can lead to gastrointestinal bleeding, and opioids like, which often lead to constipation. They concluded that doctors may consider adding antidepressants, such as Cymbalta to the treatment regimens for patients with osteoarthritis. The FDA requires that Cymbalta carry a black-box warning about the risk cymbalta 20 mg price suicide among people who use the antidepressant.

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How Duloxetine works Duloxetine works by increasing the levels of chemical messengers serotonin and noradrenaline, natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain. Duzela Sun Pharmaceutical Industries Ltd. Duvanta Intas Pharmaceuticals Ltd. Dulane Sun Pharmaceutical Industries Ltd. Dulotin Icon Life Sciences.

Cymbalta is used to treat depression, anxiety and other conditions prescribed by your doctor. Not valid at any other pharmacy. Walmart cards must be used at Walmart pharmacies. Prices for some drugs may be higher or vary in some states including, but not necessarily limited to, CA and MN. Walgreens cards must be used at Walgreens pharmacies. Cymbalta is an anti-anxiety medication used to treat depression and other conditions prescribed by your doctor, including anxiety, diabetic peripheral neuropathy, fibromyalgia, and chronic muscle.

Cymbalta is an antidepressant that possesses a strong anxiolytic and analgesic effect. Three dosage cymbalta 20 mg price of Cymbalta can be usedfor treatment of neurological and mental diseases: 20 mg, 30 mgand 60 mg. Cymbalta capsules contain Duloxetine as hydrochloride HCl. Cymbalta helps reduce anxiety or depression, and helps to normalize pain sensitivity, as well. Cymbalta capsules are approved for the pharmacotherapy of