80 mg lipitor

Before you take LIPITOR, tell your doctor about all of your medical conditions, including if you: have unexplained muscle aches or weakness drink more than 2 glasses of alcohol daily have diabetes have thyroid problems have kidney problems had a stroke are pregnant or plan to become pregnant. Muscle problems, including muscle breakdown, can be serious in some people and, rarely, cause kidney damage that can lead to death. Tell your doctor right away if you have: unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel more tired than usual while you take LIPITOR. Your doctor may do further tests to diagnose the cause of your muscle problems. Your chances of getting muscle problems are higher if you: are taking certain other medicines while you take LIPITOR drink large amounts of grapefruit juice are 65 years of age or older have thyroid problems hypothyroidism that are not controlled have kidney problems are taking higher doses of LIPITOR Liver problems. Exercise regularly and make healthy food choices to maintain healthy body weight.

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The concomitant use of higher doses of atorvastatin with certain drugs such as cyclosporine and strong cytochrome P 3A4 CYP3A4 inhibitors e. The risk of myopathy during treatment with drugs in this class is increased with concurrent administration of the drugs listed in Table 2. Physicians considering combined therapy of LIPITOR with any of these drugs should carefully weigh the potential benefits and risks and should carefully monitor patients for any signs or symptoms of muscle pain, tenderness, or weakness, particularly during the initial months of therapy and during any periods of upward dosage titration of either drug. Lower starting and maintenance doses of atorvastatin should be considered when taken concomitantly with the aforementioned drugs. Prescribing recommendations for interacting agents are summarized in Table 2 see Dosage and Administration 2. LIPITOR therapy should be temporarily withheld or discontinued in any patient with an acute, serious condition suggestive of a myopathy or having a risk factor predisposing to the development of renal failure secondary to rhabdomyolysis e. The effects, if any, on the pituitary-gonadal axis in premenopausal women are unknown. Caution should be exercised if a statin is administered concomitantly with drugs that may decrease the levels or activity of endogenous steroid hormones, such as ketoconazole, spironolactone, and cimetidine.

Lipitor comes as an buy augmentin 625 tablet. The drug is a brand-name medication. For a comprehensive look at Lipitor, see this article. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. Your doctor will determine the best dosage to fit your needs.

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However, physicians appear reluctant to use high doses of statins. A retrospective analysis of pooled data from 49 clinical trials of atorvastatin in 14, patients treated for an average period of 2 weeks to 52 months was conducted. Serious adverse events were rare and seldom led to treatment withdrawal with any dose. Treatment-associated myalgia was observed in 1. The incidence of treatment-associated adverse events for atorvastatin 80 mg was similar to that of atorvastatin 10 mg and placebo. My Bibliography Add to Bibliography.

Lipitor can also raise the levels of HDL cholesterol good cholesterol in your blood. The drug is sometimes prescribed to people with an existing heart condition to lower their risk of experiencing a heart attack or other cardiac event. Additionally, Lipitor may be prescribed as a preventive drug for people with type 2 diabetes, high blood pressure hypertension, a history of smoking, or other conditions that could increase their risk for heart complications. In, the company denied liability for lawsuits by women who claimed that Lipitor gave them type 2 diabetes, stating that the women may have other risk factors that make them vulnerable to the disease, such as high blood pressure or obesity. In a study of more than, patients newly treated with a statin, researchers found that Lipitor presented the highest 80 mg lipitor risk. Before taking Lipitor, tell your doctor if you have a thyroid disorder, muscle pain or weakness, a history of liver or kidney disease, or if you drink more than two alcoholic beverages a day.

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Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. Atorvastatin was patented in, and approved for medical use in the United States in The primary uses of atorvastatin is 80 mg lipitor the treatment of dyslipidemia and the prevention of cardiovascular disease: 9. Statins predominantly simvastatin have been trialled in combination with fibrates to manage dyslipidemia in patients who also have type 2 diabetes, and a high cardiovascular disease risk, however, there is limited clinical benefit noted for most cardiovascular outcomes 35 While many short half-lives statin medications should be administered in the evening for optimal effect, atorvastatin can be dosed at any time of day due to its long half-life profile, as long as it is continually dosed once daily at the same time to enhance better adherence. Some studies found evening dose of both short and long half-life statins was significantly superior to morning dose for lowering LDL-C.

The mg dose should not be used in new patients or those taking lower doses of the drug who need to lower their cholesterol further, the agency said in a safety alert, which outlined label changes and dose limitations for the drug. As I see it, this is a general statin problem, not just a problem. Cam Patterson, MD, a cardiologist at the University of North Carolina at Chapel Hill, noted that most patients who are taking simvastatin are not taking the mg dose. Patterson indicated that lower cost might be the only reason to continue using simvastatin, as the more potent statins are better at reducing cardiac events and may carry a lower risk of side effects. Those labels, in addition to that of the simvastatin-niacin combination Simcor -- which is not available with the highest dose of the statin -- have also been changed to reflect a greater number of medications that may interact with simvastatin to increase the risk of myopathy. According to the new label, posaconazole Noxafil should not be used with any dose of simvastatin.

The starting dose and maintenance doses of LIPITOR should be individualized according to patient characteristics such as goal of therapy and response. Doses should be individualized according to the recommended goal of therapy see Indications and Usage 1. The combination of HMG-CoA reductase inhibitors statins and fibrates should generally be used with caution see Warnings and Precautions 5. In patients taking clarithromycin, itraconazole, elbasvir plus grazoprevir, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, fosamprenavir plus ritonavir or letermovir therapy with LIPITOR should be limited to 20 mg, and appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used. When co-prescribing atorvastatin with other protease inhibitors, appropriate clinical assessment is recommended to ensure that the lowest dose necessary of LIPITOR is used see Warnings and Precautions 5. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.