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Women should be aware of increased susceptibility to vaginal yeast infections. Regular general health checks with a General Practioner are important, including glycosylated haemoglobin levels (this test gives a measure of how well blood glucose concentration is being controlled), cholesterol levels (including high-density lipoproteins [HDL]) and kidney function. Eyes should be examined for signs of retinal disease annually so that treatment can begin before damage to vision occurs. The endocrine system is complex, involving many glands and hormones, which are interconnected by feedback mechanisms.
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For example paramedics can administer certain named drugs in emergency situations. Podiatrists and chiropodists can administer certain POM, including local anaesthetics. The Medicines Act divides drugs into three major categories: Each category is subject to different legal requirements. This is a list of all medicines that have been produced under licence or are composed of materials that are exempt from the licensing arrangements. GSL items may be supplied from premises other than a registered pharmacy, for example a shop or supermarket and by persons other than a pharmacist and without supervision of a pharmacist.
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A suggestion for the exemption list has been made for the use of corticosteroids in acute musculoskeletal treatment, which would allow non-prescribing physiotherapists to inject joints and tendons without always having to refer to a doctor or a PGD. This would improve patient access to treatment. In womens health, exemptions could be made for the supply andor administration of anti-cholinergic drugs for overactive bladder symptoms in an NHS setting. The physiotherapy profession could aim to follow the path taken by the nursing profession, from first being able to prescribe a few drugs, to widening access to where they are today with independent prescribing.
Mechanisms of acquired resistance to cancer chemotherapy include: decreased uptake of drug into cells, or increased expulsion from cells; increased production of substances that can inactivate the drug; increased activity of DNA repair enzymes; increased metabolism and inactivation of the drug; reduced conversion of drug into its active form. All drugs used to treat cancer have a narrow therapeutic ratio and considerable potential for causing serious harm.
This can lead to differences in the rate at which a drug is metabolized and therefore after a given period of time, plasma levels will be different in different individuals. The administration of more than one drug simultaneously can potentially alter the actions of any of them.
A large number of drugs have a high affinity for albumin and other plasma proteins. Binding to plasma protein inhibits distribution outside the blood since only unbound drug will be further distributed.
Loperamide is prescribed to counteract gastrointestinal side effects of therapeutic radiography. Adverse effects of loperamide are constipation, abdominal cramps, drowsiness and dizziness. Miscellaneous drugs used as adjuncts to radiography are summarized Wounds may become infected and need topical antibacterial treatment.
An example of a benzamide derivative is amisulpiride. These are the newer drugs used to treat schizophrenia. Atypical anti-psychotic drugs are recommended for newly diagnosed schizophrenics and those who cannot tolerate other drugs or who are not getting adequate control from other drugs. All are thought to improve negative as well as positive symptoms of schizophrenia in addition to causing fewer motor side effects and are less likely to affect prolactin secretion. Examples of atypical anti-psychotic drugs are clozapine, risperidone, olanzapine and quetiapine.
Such fungal infections of the skin are known as tinea: Tinea pedis is infection of the foot (athletes foot); tinea corporis is infection on the body and tinea capitis is infection of the scalp. Fungal infection of the nails is known as tinea unguium or onychomycosis. Superficial fungal infections can usually be treated with topical preparations, but systemic antifungal drugs can be necessary for nail and scalp infections, or if skin infection is extensive and unresponsive to topical therapy.
Toxoplasma encephalitis is a common complication of HIV infection. Pneumocystis pneumonia is an opportunistic lung infection almost exclusively seen in patients with HIV. It is often the presenting symptom and a leading cause of death in patients with HIV. An organism called Pneumocystis cariniiwhich used to be classified as a protozoan, causes this type of pneumonia. However, the organism appears to have characteristics of both protozoa and fungi so its classification is currently uncertain.
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It is possible that β-blockers work, at least partially, by some central action in the cardiovascular control centres of the brain. β-blockers also block receptors in the peripheral blood vessels, kidney and bronchi. The main effects of this are vasoconstriction in skeletal muscles causing cold extremities and reduced renin secretion, which would limit the formation of angiotensin II. β-blockers can precipitate asthma and should not be used in people with asthma. They should be used with caution in people with diabetes because the β-blocking effect can mask warning signs of hypoglycaemia.
Authored by Dr. Linda Suriyakham, PHD
Five different peptides 6—18 residues with chain lengths shorter than the required minimum to span the bacterial cell membrane as monomeric helices were designed in order to elucidate whether variation in chain length exerted differences in their mode of action.
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Casodex is taken either through injection or from a tiny chip that is implanted under the skin.