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Ref document number: Country of ref depakote 800mg EP. Valproic acid and its derivatives are indicated for the treatment of different types of epilepsy, for the treatment of acute manic or mixed episodes associated with bipolar disorder, and for prophylaxis of migraine headaches. Particularly, a complex constituted by a 1: 1 molar relationship of valproic acid and sodium valproate divalproex sodium has recently reached some preference in the market. Both tablets divalproex-DR and divalproex-ER are supplied in dosage strengths containing divalproex sodium equivalent to and mg of valproic acid.

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