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Multivariate adjusted odds ratio estimates did not vary significantly from the univariate estimates. In addition, no association between loratadine use and hypospadias was determined when cases with multiple major defects were excluded or when different exposure periods were examined. In November, loratadine was approved by the Food and Drug Administration for over-the-counter use 7. The results of this analysis might be useful for women and health-care providers to address concerns about loratadine use and hypospadias.
Women should continue to consult their health-care providers before using any medications during pregnancy. Future studies of medications and birth defects, possibly using NBDPS, are needed to address some of the current knowledge gaps on the effects of medication use during pregnancy. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U. Department of Health and Human Services. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.
Evaluation of an Association Between Loratadine and Hypospadias United States, Hypospadias is a birth defect that affects approximately seven in 1, male infants in the United States. Use of antihistamine drugs in early pregnancy and delivery outcome. J Matern Fetal Neonatal Med ; Ask your pharmacist what to do with unused medications. These measures will help protect the environment. Full list of active substances and excipients.
Lactose monohydrate, microcrystalline cellulose, corn starch, magnesium stearate. Allergy is an overreaction of our body to substances it considers harmful, allergens. Allergens are the factors and substances triggering allergy and associated disorders. The allergic reaction refers to all symptoms appearing a few minutes or hours after exposure to allergens. These allergens come from plants, animal hair, food, dust mites, molds or are substances of occupational origin.
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Authored by Dr. David D Passarelli, DC