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Common side effects include weight gain, movement disorders, dizziness, feeling tired, constipation, and dry mouth. Olanzapine was patented in and approved for medical use in the United States in The first-line psychiatric treatment for schizophrenia is antipsychotic medication; with olanzapine being one such medication. National Institute for Health and Care Excellence, the British Association for Psychopharmacology, and the World Federation of Societies for Biological Psychiatry suggest that there is little difference in effectiveness between antipsychotics in prevention of relapse, and recommend that the specific choice of antipsychotic be chosen based on a person's preference and the drug's side effect profile. Agency for Healthcare Research and Quality concludes that olanzapine is not different from haloperidol in the treatment of positive symptoms and general psychopathology, or in overall assessment, but that it is superior for the treatment of negative and depressive symptoms. In a comparison of 15 antipsychotic drugs in schizophrenia, olanzapine was ranked third in efficacy. Olanzapine caused less extrapyramidal side effects, less akathisia, but caused significantly more weight gain, serum cholesterol increase, and triglyceride increase than haloperidol. Olanzapine is recommended by the National Institute of Health and Care Excellence as a first line therapy for the treatment of acute mania in bipolar disorder. The Network for Mood and Anxiety Treatments CANMAT recommends olanzapine as a first line maintenance treatment in bipolar disorder and the combination of olanzapine with fluoxetine as second line treatment for bipolar depression.

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Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment. Olanzapine is not approved by the Food and Drug Administration FDA for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking olanzapine. Olanzapine is used to treat the symptoms of schizophrenia a mental illness that causes disturbed or unusual seroquel tab 50mg, loss of interest in life, and strong or inappropriate emotions in adults and teenagers 13 years of age and older. It is also used to treat bipolar disorder manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods in adults and teenagers 13 years of age and older.

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