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Antipsychotics originally were thought only to help people with psychosis. However, since their initial development, further research has indicated that this class of drugs could also be helpful in mood stabilizing. Atypical antipsychotics offer superior safety and similar efficacy compared with conventional agents in adults with psychotic disorders. For this reason, atypical antipsychotics have been increasingly used in children and adolescents. Five agents currently have FDA-approved indications for use in children and adolescents: risperidone, aripiprazole, olanzapine, paliperidone, and quetiapine.

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Recommended to establish tolerability of PO risperidone before initiating treatment with IM risperidone. Cardiac disorders: Tachycardia, sinus bradycardia, sinus tachycardia, atrioventricular block first degree, bundle branch block left, bundle branch block right, atrioventricular block. Eye Disorders: Vision blurred, oculogyration, ocular hyperemia, eye discharge, conjunctivitis, eye rolling, eyelid edema, eye swelling, eyelid margin crusting, dry eye, lacrimation increased, photophobia, glaucoma, visual acuity reduced. Gastrointestinal disorders: Dysphagia, fecaloma, fecal incontinence, gastritis, lip swelling, cheilitis, aptyalism. General disorders: Thirst, gait disturbance, chest pain, influenza-like illness, pitting edema, edema, chills, sluggishness, malaise, face edema, discomfort, generalized edema, drug withdrawal syndrome, peripheral coldness, feeling abnormal.

It can cause significant impairment in all areas of functioning in patients of all ages 3. It is important to note that impairment due to ADHD will continue into adulthood and will require treatment 4. The level of impairment of preschoolers with ADHD is similar to that of affected school age children 6. Other problems include preschool expulsion, difficulty in maintaining babysitters or childcare and as a result, missed family work days and personal time 8. This group also had higher rates of emotional adverse effects including lability, crabbiness, irritability, and proneness to crying compared to older children 4

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It is important to understand the risks and benefits of pill splitting before you recommend the practice to patients. Many psychotropics come in multiple strengths, and one larger pill often costs less than 2 smaller pills of equivalent dosage. Pill splitting allows you to prescribe a lower strength to gradually titrate dosages up or taper them down. This practice can prevent side effects and improve adherence because a lower dose may have a more favorable pharmacokinetic profile. Patients might better tolerate half a pill taken twice daily rather than an entire pill once daily. A smaller dose may prevent a spike in serum level, which could aid tolerability.

How Risperidone works Risperidone is an atypical antipsychotic. It works by affecting the levels of chemical messengers dopamine and serotonin to improve mood, thoughts and behavior. Common side effects of Risperidone Insomnia difficulty in sleeping, Parkinsonism, Sedation, Dizziness, Weight gain, Akathisia inability to stay still, Anxiety, Gastrointestinal symptom, Increased prolactin level in blood. Risdone Risperdal 20mg Pharmaceuticals Ltd. Risperdal Consta Janssen Pharmaceuticals. Respidon Torrent Pharmaceuticals Ltd.

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Meet your Best of the Best Pharmacy Award winners! It is approved by the Food and Drug Administration FDA for the treatment of schizophrenia, bipolar mania, and irritability associated with autism. Risperidone is sometimes used off-label, meaning without an FDA indication, for Tourette syndrome, aggression in patients with dementia, obsessive-compulsive disorder, major depressive disorder, and other psychiatric conditions. These antipsychotic drugs help regulate mood and behavior by balancing levels of dopamine and serotonin in the brain. While risperidone is effective for improving psychotic symptoms, it may also cause bothersome side effects. Drowsiness, weight gain, sexual dysfunction, elevated blood pressure, and high cholesterol, blood sugar, and prolactin levels are common side effects.

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In these situations, psychostimulant-antipsychotic combinations can be a useful strategy. Child psychiatry; Methylphenidate; Risperidone; Psychostimulant-antipsychotic combination; Attention deficit hyperactivity disorder. Methylphenidate MPH is the first choice pharmacological drug for the treatment of ADHD because of its well-established activity on hyperactivity and inattention. Bitherapies seem well-tolerated, and beneficial effects have been even found on appetite and sleep disturbances. However, these combinations are not exempt of risks and there seem to be more serious side effects such as dyskinesia. In these three clinical situations, the children received: firstly RIS for the first patient or MPH in the other two situations, before bitherapy.

The chemical designation is 3-ethyl-6,7,8,9-tetrahydromethyl-4H-pyridopyrimidinone. Risperidone is a white to slightly beige powder. Efficacy was established in 4 short-term trials in adults, 2 short-term trials in adolescents ages 13 to 17 years, and one long-term maintenance trial in adults. Efficacy was established in 2 short-term trials in adults and one short-term trial in children and adolescents ages 10 to 17 years. Efficacy was established in one short-term trial in adults. Efficacy was established in 3 short-term trials in children and adolescents ages 5 to 17 years.