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Randomized clinical trials have established the benefits of statin therapy in acute coronary syndromes ACS via their pleiotropic effects. The primary endpoint was the percent change from baseline in low-density lipoprotein cholesterol LDL-C levels at 6 and 12 weeks of treatment. Other lipid parameters, high sensitive C-reactive protein hsCRP, glycosylated hemoglobin, and clinical biochemical parameters were also assessed. Author links open overlay panel Chetan P. Krishnamani f Ashwani Mehta g P. Under a Creative Commons license.

Rosuvastatin is available as the brand-name drug Crestor. This drug may be used as part of a combination therapy. This means you may need to take it with other medications. It also reduces your triglyceride level fats in your blood. These blockages can cause serious problems, including heart attack or stroke.

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Products that are in a Supply Only state will be available for dispensing, but not for prescribing. Pharmaceutical Benefits Scheme. Blooms the Chemist Rosuvastatin a. Pharmacor Rosuvastatin 40 a. Cavstat SO Products that are in a Supply Only state will be available for dispensing, but not for prescribing.

What if I am taking other medicines? Are there any side effects? Even though you may have normal cholesterol, CRESTOR can also be used to reduce the risk of you having a stroke or heart attack if you are a man 50 or more years old or a women 60 or more years old and have at least 2 risk factors for having a heart attack or stroke, such as high blood pressure, low levels of good cholesterol, smoking or a family history of premature coronary heart disease. During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect CRESTOR.

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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This leaflet has been written to help you get the best effect from your medicine. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever. Also tell your doctor or pharmacist if you have a muscle weakness that is constant. You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels.

Cardiology 1 June ; 99 3: — It is approved for use at doses of 10—40 mg once daily to reduce low-density lipoprotein LDL cholesterol, increase high-density lipoprotein HDL cholesterol and improve other lipid measures in dyslipidemic patients. Rosuvastatin also produces marked elevations in HDL cholesterol and maintains this effect across the dose range. Rosuvastatin favorably modifies triglycerides, LDL cholesterol and other lipid measures in patients with hypertriglyceridemia or mixed dyslipidemia, including diabetic patients, and may constitute a monotherapy option for many such patients. Rosuvastatin is well tolerated when used alone or in combination, exhibiting a safety profile similar to that of other available statins. Rosuvastatin offers considerable advantages for use in routine clinical practice.

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It is used to lower cholesterol and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke. Crestor 40mg Tablet is a widely prescribed medicine and is regarded as safe for long-term use. It can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at 40 mg crestor same time each day. Most people with high cholesterol do not feel ill, but stopping your medicine may increase your cholesterol levels, making your condition worse and increasing your risk of heart disease and stroke.

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Both drugs work in the same way, helping to block a chemical necessary for making cholesterol. In turn, they help lower cholesterol, reduce risk for cardiac events and slow the 40 mg crestor of heart disease. Over 1, patients with heart disease participated in this study — half of whom took the maximum daily dose of atorvastatin 80 mg while the other half were prescribed the maximum daily dose of rosuvastatin 40 mg. Based on findings, atorvastatin and rosuvastatin are equally as safe and effective in lowering cholesterol and possibly reversing plaque build-up with aggressive treatment. Patients and doctors should always discuss the possible side effects of taking cholesterol-lowering drugs.

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