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Drink extra water while on this medicine. Adults should try to drink cups 48 to 64 oz. It is important that you keep taking each dose of this medicine on time even if you are feeling well. If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Increase the daily dose by 50 mg once per week during weeks 2, 3, and 4. Increase the daily dose by mg once per week during weeks 5 and 6; administer total daily dose in 2 divided doses. The recommended final dose, mg per day PO in 2 divided doses, is achieved during week 6. Initially, 25 mg PO once daily in the evening. If tolerated, may increase the dosage to 25 mg PO twice daily during week 2 of therapy.

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Give in two equally divided doses. Initially 25mg once daily in the PM, then 25mg twice daily, then 25mg in the AM and 50mg in the PM, then 50mg twice daily. Hemodialysis: may need extra dose. Discontinue if acute myopia, secondary angle-closure glaucoma occur. Consider discontinuing if visual field defects occur. Maintain adequate hydration and caloric intake; avoid ketogenic diets. Inborn errors of metabolism or reduced hepatic mitochondrial activity: increased risk of hyperammonemia; measure ammonia levels if encephalopathic symptoms occur. Monitor closely for oligohidrosis and hyperthermia esp. Suicidal tendencies monitor.

Monotherapy in adults, adolescents and children over 6 years of age with partial seizures with or without secondary generalised seizures, and primary generalised tonic-clonic seizures. Adjunctive therapy in children aged 2 years and above, adolescents and adults with partial onset seizures with or without secondary generalization or primary generalized tonic-clonic seizures and for the treatment of seizures associated with Lennox-Gastaut syndrome. Topiramate is indicated in adults for the prophylaxis of migraine headache after careful evaluation of possible alternative treatment options. Topiramate is not intended for acute treatment. It is not necessary to monitor topiramate plasma concentrations to optimize therapy with Topamax.

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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This product is available in multiple strengths. Do not pass it on to others. This includes any possible side effects not listed in this leaflet. What is in this leaflet 1. What Topamax is and what it is used for 2.

The asterisk indicates patients who did not provide at least 1 postbaseline efficacy assessment. Mean least squares value change from baseline in monthly migraine frequency. Missing data were computed based on the frequency of migraines observed before discontinuation. Mean least squares value percentage change from baseline in body weight. Objective To assess the efficacy and safety of topiramate as a migraine-preventive therapy.

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It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. If you have any concerns about taking this medicine, ask your doctor or pharmacist. It can also be used for the prevention of migraines in adults. Ask your doctor if you have any questions about why this medicine has been prescribed for you.

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Not valid for patients using Medicare, Medicaid, or other government-funded programs to pay for their medications. Offer not valid in CA and MA. There is no income requirement. See program requirements below. This program is in no way an extension of medical treatment provided by healthcare professionals to individual patients. Janssen Pharmaceuticals, Inc.

Topiramate belongs to a class of medicines known as anticonvulsants. These drugs are anti-epileptics. It is a primary choice of medicine for epileptic patients. Topiramate is useful for migraines. It is used to prevent migraine headaches and not to treat the headaches. The primary use of Topiramate is an anti-epileptic or anti-convulsant.