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Antibiotic trimethoprim and sulfonamide combination in a ratio. Sulfamethoxazole inhibits the synthesis of dihydrofolic acid. Trimethoprim inhibits thymidine and DNA synthesis. Hematologic — pancytopenia, agranulocytosis, anemia, thrombocytopenia. Renal — transient blood urea and creatinine elevations, crystalluria, acute interstitial nephritis. CNS — headache, confusion, depression, aseptic meningitis.

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WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Sulfamethoxazole-Trimethoprim injection is a sulfonamides that is FDA approved for the treatment of urinary tract infections, acute otitis media in pediatric patients, acute exacerbations of chronic bronchitis, shigellosis, pneumocystis jiroveci pneumonia, prophylaxis against P. Common adverse reactions include nausea, vomiting, anorexia, and allergic skin reactions as rash and urticaria. There is no FDA guidance on use of Sulfamethoxazole-Trimethoprim injection during labor and delivery. There is no FDA guidance on the use of Sulfamethoxazole-Trimethoprim injection with respect to specific gender populations. There is no FDA guidance on the use of Sulfamethoxazole-Trimethoprim injection with respect to specific racial populations.

Earn 0 points with this purchase. Sulfamethoxazole and Trimethoprim SMZ-TMP Tablets are a combination antibiotic used to treat respiratory, urinary tract, skin, or gastrointestinal infections, and other conditions. Sulfamethoxazole is a sulfonamide antibiotic that limits the growth of bacteria. Sulfonamides inhibit synthesis of folic acid, important to bacterial DNA synthesis. Trimethoprim works by starving the bacteria of nucleotides necessary for DNA replication. Do not use in pregnant or nursing animals.

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May be administered without regard to meals. Administer with food, water, or milk to minimize gastric irritation. Rapid or direct IV injection must be avoided. Dilute 5 ml of the concentrate for injection in ml of D5W. For fluid-restricted patients, 75 ml of D5W may be used.

Common side effects include nausea, vomiting, rash, and diarrhea. Co-trimoxazole was claimed to be more effective than either of its components individually in treating bacterial infections, although this was later disputed. Co-trimoxazole decreases the risk of recurrence of retinochoroiditis. Organisms against which co-trimoxazole can be effective include The only notable nonsusceptible organisms are Pseudomonas aeruginosa, the mycoplasmae and Francisella tularensis the causative organism of tularaemia. Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C and American pregnancy category D.

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The drug is a combination of two antibiotics: It's one part trimethoprim a synthetic drug, and five parts sulfamethoxazole a sulfonamide drug. The drug is made by Mutual Pharmaceutical Co. Though rare, the use of sulfonamides can cause severe and potentially fatal reactions, such as Stevens-Johnson syndrome. As with most other antibiotics, Bactrim may cause prolonged diarrhea resulting from a difficult-to-treat Clostridium difficile C. The drug has a warning that if you take it when you're pregnant, it can cause such birth defects as urinary tract defects, cleft lip or palate, or club feet. It should only be used during pregnancy if the benefits clearly outweigh the potential harms to the unborn child.

Bactrim sulfamethoxazole and trimethoprim DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus MRSA, and other bacterial infections susceptible to this antibiotic. Trimethoprim is 2,4-diamino 3,4,5-trimethoxybenzyl pyrimidine. It is a white to light yellow, odorless, bitter compound with a molecular weight of Sulfamethoxazole is N 1 - 5-methylisoxazolyl sulfanilamide. It is an almost white, odorless, tasteless compound with a molecular weight of BACTRIM is indicated in the treatment of Pneumocystis jirovecii pneumonia in adults and pediatric patients two months of age and older.

Bactrim is the brand name of a combination medicine that contains the antibiotics sulfamethoxazole and trimethoprim. It works by halting the growth of bacteria. You should not use this medicine if you are allergic to sulfamethoxazole or trimethoprim, or if you have Do not use if you are pregnant. Tell your doctor if you become pregnant. This medicine should not be given to a child younger than 2 months old.