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Decreases excitability of middle-ear labyrinth and depresses conduction in vestibular-cerebellar pathways. May repeat q 24 hours for duration of travel. CNS: drowsiness, fatigue, confusion, excitement, euphoria, nervousness, restlessness, insomnia, vertigo, visual and auditory hallucinations, seizures. Anticholinergics including some antihistamines, antidepressants, atropine, haloperidol, phenothiazines: additive anticholinergic effects. Pharmacologic class: Anticholinergic Therapeutic class: Antiemetic, antivertigo drug Pregnancy risk category B.
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