Tofranil 5 mg

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Ask your doctor if you have any questions. The dose of this medicine will be different for different patients. If your dose is different, do not change it unless your doctor tells you to do so.

Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant TCA mainly used in the treatment of depression. It is also effective in treating anxiety and panic disorder. Imipramine is taken by mouth. Common side effects of imipramine include dry mouth, drowsiness, dizziness, low blood pressure, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose of the medication can result in death. Imipramine appears to work by increasing levels of serotonin and norepinephrine and by blocking certain serotonin, adrenergic, histamine, and cholinergic receptors.

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Tofranil is indicated in- Depressive illness Nocturnal enuresis in children. Tofranil is an original tricyclic antidepressant, a member of the dibenzazepine group of compounds. The mechanism of action of Tofranil is not definitely known. However, it does not act primarily by stimulation of the central nervous system. The clinical effect is hypothesized as being due to the potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings. The mode of action of the drug in controlling childhood enuresis is thought to be apart from its antidepressant effect. Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and serotonin. It binds the sodium-dependent serotonin transporter and sodium-dependent norepinephrine transporter reducing the reuptake of norepinephrine and serotonin by neurons. Depression has been linked to a lack of stimulation of the post-synaptic neuron by norepinephrine and serotonin. Slowing the reuptake of these neurotransmitters increases their concentration in the synaptic cleft, producing knock-on effects in protein kinase signaling which is thought to contribute to changes in neurotransmission and brain physiology which relieves symptoms of depression.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as tofranil 5 mg body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

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Action Inhibits reuptake of norepinephrine and, to a lesser degree, serotonin in CNS. Unlabeled use s: Treatment of chronic pain, panic disorder, eating disorders bulimia nervosa, and facilitation of cocaine withdrawal. Contraindications Hypersensitivity to any tricyclic antidepressant. Generally not to be given in combination with or within 14 days of treatment with MAO inhibitor or during acute recovery phase of Order atarax online cross-sensitivity may occur among the dibenzazepines. Switch to oral as soon as possible.

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior suicidality in children, adolescents, and young adults in short-term studies of major depressive disorder MDD and other psychiatric disorders. Anyone considering the use of imipramine hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Tofranil, imipramine hydrochloride USP, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. It is designated dimethylamino propyl,dihydro-5 H -dibenz b,f -azepine monohydrochloride. It is freely soluble in water and in alcohol, soluble in acetone, and insoluble in ether and in benzene.

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Keep your regular appointments with your doctor. This is so your doctor can check on your progress. Imipramine can make you feel sleepy. If this happens, do not drive and do not use tools or machines. It is generally tofranil 5 mg for the treatment of depression in adults.

TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause tofranil 5 mg. In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

Nighttime enuresis, or bedwetting, is usually defined as the involuntary loss of urine during sleep after the age of 5 years. It's known to cluster in family groups — if one or both parents have had trouble with bedwetting, their children are more likely to have similar problems. Bedwetting is also more common in boys. Fifteen percent of 5-year-olds and 10 percent of 6-year-olds experience enuresis. As children mature, the number of children with enuresis problems declines at a rate of about 15 percent per year. The cause of bedwetting is not known.