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It is used to treat heart failure and atrial fibrillation and has other off-label uses. Digoxin is effective for rate control in patients with atrial fibrillation, but its influence on mortality rates is a source of controversy. Digoxin can cause many adverse events, is involved in multiple drug interactions, and can result in toxicity. Despite its limitations, however, digoxin has a place in therapy. Digoxin is a cardiac glycoside derived from the purple foxglove flower.

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Learn about the medical, dental, pharmacy, behavioral, and voluntary benefits your employer may offer. You should not use digoxin if you are allergic to it, or if you have ventricular fibrillation a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart. Tell your doctor if you are pregnant. It is not known whether digoxin will harm an unborn baby. However, having heart failure or atrial fibrillation during pregnancy may cause complications such as premature birth or low birth weight, or risk of death in both mother and baby.

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