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Enzalutamide, a potent oral androgen receptor inhibitor, improves survival in men with metastatic castration-resistant prostate cancer CRPC before and after chemotherapy. Bicalutamide, a nonsteroidal antiandrogen, is widely used to treat men with nonmetastatic or metastatic CRPC. The efficacy and safety of these drugs were compared in this randomized, double-blind, phase II study of men with CRPC. Androgen deprivation therapy was continued in both arms. The primary end point was progression-free survival PFS. Enzalutamide resulted in significant improvements in all key secondary end points: time to prostate-specific antigen progression HR, 0.

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Product introduction Casodex 50mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to casodex cost uk other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. Casodex 50mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it.

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Casodex Bicalutamide is used to treat patients suffering from prostate cancer. Uses Casodex Tenormin buy online is used to treat patients suffering from prostate cancer. This prevents the growth of the cancer cells, as they require testosterone to grow. As a result of this, the tumour shrinks. Dosage and Administration Your doctor will tell you how much Casodex Bicalutamide tablets you need to take, as well as whether you should take the 50mg tablets or the mg tablets.

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With, new cases and 39, deaths anticipated in, prostate cancer is second only to lung cancer in cancer mortality for men. Three key issues are addressed: 1 the relative effectiveness of the available methods for monotherapy orchiectomy, luteinizing hormone-releasing hormone agonists, and antiandrogens, 2 the effectiveness of combined androgen blockade compared to monotherapy, and 3 the effectiveness of immediate androgen suppression compared to androgen suppression deferred until clinical progression. Outcomes of interest are overall, cancer-specific, and progression-free survival; time to treatment failure; adverse effects; and quality of life. Two supplementary analyses were conducted for each key question: 1 meta-analysis of overall survival at 2 years questions 1 and 2 and 5 years questions 2 and 3, and 2 cost-effectiveness analysis. Total yield was 1, references. The meta-analysis combined data on overall survival using a random effects model.