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It works by decreasing the amount of acid made in the stomach. NDMA is a known environmental contaminant in the US and found in water, vegetables, dairy products, and meats. The FDA is working with regulators around the world to determine the direct source of the ranitidine impurity. The FDA is not asking for patients to stop taking ranitidine at this time.

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This is the latest step in an ongoing investigation of a contaminant known as N-Nitrosodimethylamine NDMA in ranitidine medications commonly known by the brand name Zantac. We make every effort to investigate potential health risks and provide our recommendations to the public based on the best available science. NDMA is a probable human carcinogen a substance that could cause cancer. These low levels would not be expected to lead to an increase in the risk of cancer.

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NDMA is a known environmental contaminant found in drinking water, soil, and common foods, including meats, dairy products, and vegetables. People are routinely exposed to small amounts of NDMA every day. Over time, both FDA and the European Medicines Agency have evaluated the available data and found no evidence that ranitidine causes cancer.